Programmable Antimicrobial Nanostructured Surfaces

Nguyen, T. P. T., McGiffin, D., Peleg, A. Y., Elnathan, R., Voelcker, N. H., Qu, Y. ACS Applied Materials & Interfaces DOI: 10.1021/acsami.6c12074

Abstract: Surfaces with programmable nanostructures represent a promising antimicrobial strategy that eradicates bacterial pathogens through physical membrane disruption and/or mechanically induced oxidative stress, independently of conventional antimicrobial resistance mechanisms. Despite their demonstrated and often potent in vitro efficacy, the successful clinical translation of this nanotechnology remains limited.