Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock

C Palmieri, LS Hoe, W Dyer, S Heinsar, S Rozencwaig, J Tung, N Bartnikowski, M Passmore, M Bouquet, K Hislop, E Wilson, GL Li Bassi, D Mcgiffin, J Suen, JF Fraser. J of Comp Path DOI: 10.1016/j.jcpa.2023.03.059

Introduction: Histopathological scoring is a tool by which semiquantitative data can be obtained from tissues. Many scoring systems according to specific study requirements exist, yet there is no standardized approach to score multiorgan injury in large animal models of ischaemia and shock.