Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

2022
Written By CCRG CCRG Admin

Dyer, Wayne B; Simonova, Gabriela; Chiaretti, Sara; Bouquet, Mahe; Wellburn, Rebecca; Heinsar, Silver; Ainola, Carmen; Wildi, Karin; Sato, Kei; Livingstone, Samantha; Suen, Jacky Y; Irving, David O; Tung, John-Paul; li Bassi, Gianluigi; Fraser, John F. Intensive Care Med Exp. 2022 Apr 4;10(1):12. DOI: 10.1186/s40635-022-00439-6

Background: Fluid resuscitation is the standard treatment to restore circulating blood volume and pressure after massive haemorrhage and shock. Packed red blood cells (PRBC) are transfused to restore haemoglobin levels. Restoration of microcirculatory flow and tissue oxygen delivery is critical for organ and patient survival, but these parameters are infrequently measured.

CCRG CCRG Admin
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