High-Flow Nasal Oxygen Therapy After Cardiac Surgery

Litton, E., Parke, R., McGuinness, S., Dawson, S., Villar, S., Shetty, S., Fox-Rushby, J., Coombes, J., Norman, R., Murphy, G., Affandi, J., Ahmed, A., Bottrill, F., Chiu, Y., Churchill, L., Dash, S., Delaney, A., Duckworth, M., Earwaker, M., Evans, C., Hoppington, A., Kunst, G., Maiorana, A., Martinez, G., McDonald, A., Mohammed, A., Orford, N., Pilcher, D., Ramanan, M., Reid, C., Senthuran, S., Shaw, M., Shelley, B., Singh, H., Steele, C., Temple, E., Veltman-Grisenthwaite, M., Yadav, S., Zimbler, N., Zochios, V., Klein, A. JAMA Network Open DOI: 10.1001/jamanetworkopen.2026.5447

Abstract: High-flow nasal oxygen therapy (HFNOT) is used for noninvasive respiratory support following cardiac surgery despite uncertainty about its clinical effectiveness or associated costs.

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Finding the Limits of Hypothermic Oxygenated Perfusion