A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by the Delphi method

Masi, P., Abrams, D., Ait Hssain, A., Balik, M., Barrett, N.A., Broman, L.M., Camporota, L., Chen, Y.-S., Combes, A., De Backer, D., Del Sorbo, L., Diaz, R., Donker, D.W., Douflé, G., Fan, E., Fraser, J.F., Giani, M., Giraud, R., Grasselli, G., Hraiech, S., Lorusso, R., MacLaren, G., Marcus, J.E., Martucci, G., Mendes, P.V., Ohshimo, S., Paiva, J.-A., Park, S., Ramanathan, K., Riera, J., Roncon-Albuquerque Jr, R., Salazar, L., Schmidt, M., Shah, A., Shekar, K., Supady, A., Taccone, F.S., Tonna, J.E., Yeung Ng, P., Yusuff, H., Luyt, C.-E. Intensive Care Medicine. DOI: 10.1007/s00134-025-08269-2

Abstract: Nosocomial infections are common in patients receiving extracorporeal membrane oxygenation (ECMO), with ECMO cannula-site infections (ECMO-CSI) being the most frequent infections directly related to the ECMO run. These infections can significantly impact patient outcomes. Currently, no adult guidelines exist for the prevention, diagnosis, and/or treatment of peripheral ECMO-CSI, resulting in heterogeneity in both clinical practice and research findings.