Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation

Gandini, L., Liu, K., Passmore, M.R., Chan, C.H.H., Wilson, E.S., Ijuin, S., Milani, A., Hyslop, K., White, N., Perera, B., Obonyo, N., Bouquet, M., Li Bassi, G., Fraser, J.F., Suen, J.Y. ASAIO Journal. DOI: 101.1097/MAT.0000000000002644

Abstract: Hydrogen has emerged as a therapeutic agent in inflammatory critical illnesses due to its potential to modulate inflammation and oxidative stress. However, its role in extracorporeal membrane oxygenation (ECMO), a life-saving intervention for severe cardiorespiratory failure associated with pronounced inflammation and oxidative stress, remains largely unexplored.