Cardiac surgery modulates leucocyte subsets and inflammatory mediators

Perros, A., Rooks, K., Chong, F., Engkilde-Pedersen, S., Esguerra-Lallen, A., Hewlett, E., Faddy, H., Naidoo, R., Tung, J., Fraser, J., Tesar, P., Ziegenfuss, M., Smith, S., Flower, R., Dean, M. Immunology Letters DOI: 10.1016/j.imlet.2026.107187

Abstract: Leucocytes regulate the immune response through multiple pathways including cytokine release, which is critical for mediating host defences. Coronary artery bypass grafting (CABG) initiates a systemic inflammatory response that may contribute to adverse patient outcomes. Full blood counts (FBC) provide insight into patient’s haematological status, however FBC don’t provide comprehensive analysis of leucocyte subsets.