Impact of Systemic Vessel Resistance and Microaxial Pump Flow Level on Left Ventricular Workload

Nonaka, H., Yuan, L., Wu, E., Bösch, J., Garbutt, M., Kanagarajan, D., Suen, J., Benitez, J., Pellegrino, V., Fraser, J. ASAIO Journal DOI: 10.1097/MAT.0000000000002722

Abstract: The transvalvular microaxial flow pump (mAFP) is increasingly used to unload the failing left ventricle (LV), yet the hemodynamic strategy to maximize unloading remains uncertain. Using a mock circulatory loop with an Impella CP, we tested how systemic vascular resistance (SVR) and pump flow levels influence LV workload.