Comparison of Left Ventricular Pressure-Volume Loops With Veno-Arterial Extracorporeal Membrane Oxygenator Support

Wu, E., Boesch, J., Nonaka, H., Djelovic, C., Wickramarachchi, A., Benitez, J., Fraser. Artificial Organs DOI: 10.1111/aor.70163

Abstract: The hemodynamic consequence of increasing veno-arterial extracorporeal membrane oxygenator (V-A ECMO) flow on left ventricular (LV) loading is controversial, with in vivo studies reporting conflicting results on left ventricular distension. We investigated increased V-A ECMO flow on LV pressure-volume characteristics under varying cardiac and volume conditions using a repeatable in vitro mock circulation loop (MCL).