Australasian Resuscitation In Sepsis Evaluation

Howe, B.D., Macdonald, S.P.J., Arendts, G., Bellomo, R., Burcham, J., Delaney, A., Egerton-Warburton, D., Fatovich, D., Fraser, J.F., Higgins, A., Jones, P., Keijzers, G., Milford, E., Udy, A.A., Williams, P., Young, P., Peake, S.L. BMJ Journals DOI: 10.1136/bmjopen-2025-101215

Abstract: International consensus guidelines support the initial administration of 30 mL/kg of intravenous fluids for haemodynamic resuscitation of newly diagnosed septic shock. Practice variation exists between the volume of fluids administered and timing of vasopressor commencement. The optimal approach in patients with septic shock is uncertain.