In vivo isolated lung perfusion: an innovative platform for assessing lung injury propagation in ARDS

Written By CCRG

Fior, G., Lloyd, B., Liu, K., Milani, A., Obonyo, N., Hoshino, K., Nonaka, H., Abbate, G., Portatadino, S., Panduru, R., Hyslop, K., Passmore, M., Meechan-Brown, C., Redmond, K., Slaughter, R., Garlick, B., McGiffin, D., Suen, J., Fraser, J., Li Bassi, G. Intensive Care Medicine Experimental DOI: 10.1183/13993003.congress-2024.PA845

Abstract: In acute respiratory distress syndrome (ARDS), injured alveoli are flooded with fluids laden with inflammatory mediators. The role of these inflammatory biofluids in propagating lung injury when displaced through the airways, namely biofluid-induced lung injury (BILI), has not been fully investigated.

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