A mock circulation loop to evaluate differential hypoxemia during peripheral venoarterial extracorporeal membrane oxygenation

2022
Written By CCRG

Rozencwajg S, Wu EL, Heinsar S, Stevens M, Chinchilla J, Fraser JF, Pauls JP Perfusion DOI 10.1177/02676591211056567

Abstract: Peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) creates a retrograde flow along the aorta competing with the left ventricle (LV) in the so-called 'mixing zone' (MZ). Detecting it is essential to understand which of the LV or the ECMO flow perfuses the upper body - particularly the brain and the coronary arteries - in case of differential hypoxemia (DH). We described a mock circulation loop (MCL) that enabled experimental research on DH.

CCRG
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Design, development and preliminary assessment in a porcine model of a novel peripheral intravenous catheter aimed at reducing early failure rates
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Highlights from the Asia-Pacific Extracorporeal Life Support Organization 2021 Conference